高强度紫外LED技术为研究实验室的净化和灭活带来了新的机遇。通过适当剂量的紫外光,微生物和生物材料都能失活。Phoseon的 KeyPro™ high-irradiance ultraviolet LED system ideally suits microbiology labs that need to quickly and reliably inactivate viruses, or for labs that require decontamination for high fidelity RNA library prep, sequencing, and PCR.
Phoseon的专利技术 半导体光矩阵(SLM)™技术 使得KeyPro系统能够提高实验室的生产力。KeyPro系统可以在5分钟内完成实验室污染物的完全灭活,成本仅为传统方法的一小部分。
KeyPro可以让研究人员对微孔板进行去污,灭活病毒,并对实验室器皿表面进行消毒,防止细菌和病毒侵入。初步数据表明,高强度紫外线可以被调整为部分或完全灭活病毒,而不破坏识别特征。保留识别特征对于现有的病毒灭活方法来说是一个挑战。
KeyPro灭活的RNase,特别是RNase A,在没有长期热处理或刺激性化学品的情况下,很难不可逆地灭活。这种方法可能与普通实验室材料不兼容,或使后续生化反应复杂化。用汞弧灯源快速、完全、不可逆地灭活RN酶A,由于目标波长的功率输出低,而且需要过滤对灭活无益的有害波长,因此很难实现。
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