Phoseon’s high-intensity UV LED technology offers rapid and reliable disinfection for laboratory surfaces and equipment. Phoseon’s KeyPro™ light engine disinfects even highly-resistant microorganisms such as Clostridium difficile. In third-party testing, Phoseon’s high intensity UV LED technology effectively inactivated C. diff spores by 5.79 log10 in seconds. Clostridium difficile spore transmission from contaminated surfaces is a continuing problem for health care facilities. In a recent study from Phoseon, high-intensity UV LED was used to rapidly inactivate Clostridium difficile spores.
High-intensity UV LED 275nm alone and 275nm+365nm combination, wavelengths targeted to protein disulfide functional groups, drive a greater than 5 log (5.79 log) CFU reduction of Clostridium difficile spores on a surface in less than 30 seconds. This is consistent with our results showing synergism between 275nm and 365nm high-intensity UV LED when irreversibly inactivating RNase A. Targeting protein stabilization and functional groups represents a new approach to spore inactivation. Microorganism inactivation with experimental dose response and projected time to log 6 reduction at 275 nm and 4W/cm² irradiance
KeyPro controls the light intensity for each session so that, once you develop an experiment or treatment protocol, you always get the same amount of light from the instrument. UV LED inactivation of microorganisms assures that surfaces are disinfected without the chemicals and time-consuming rinsing.